ω-3 Polyunsaturated Fatty Acids on the Prognosis of Multiple Sclerosis: The Effect of Eicosapentaenoic acid

Multiple sclerosis (MS) is a chronic neurological disease that is a major cause of disability in young adults in Europe and North America [1]. The clinical course of MS is unpredictable and varies individually, with some patients experiencing minimal impairment. The majority of patients have a form of MS referred to as relapsing-remitting MS (RRMS) characterized by periods of clinical stability that are interrupted by relapses. MS is generally considered an immune-mediated disease characterized by disseminated foci of inflammatory demyelination affecting the central nervous system (CNS). Environmental factors have been suggested as possible factors affecting both disease risk and progression in individuals with complex genetic-risk profiles [2].